Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice

Podocytes are specialized epithelial cells covering the basement membrane of the glomerulus in the kidney. The molecular mechanisms underlying the role of podocytes in glomerular filtration are still largely unknown. We generated podocin-deficient (Nphs2(−/−)) mice to investigate the function of pod...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Roselli, Séverine, Heidet, Laurence, Sich, Mireille, Henger, Anna, Kretzler, Matthias, Gubler, Marie-Claire, Antignac, Corinne
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2004
Pynciau:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC343810/
https://ncbi.nlm.nih.gov/pubmed/14701729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.2.550-560.2004
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