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Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice

Podocytes are specialized epithelial cells covering the basement membrane of the glomerulus in the kidney. The molecular mechanisms underlying the role of podocytes in glomerular filtration are still largely unknown. We generated podocin-deficient (Nphs2(−/−)) mice to investigate the function of pod...

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Publicat a:Mol Cell Biol
Autors principals: Roselli, Séverine, Heidet, Laurence, Sich, Mireille, Henger, Anna, Kretzler, Matthias, Gubler, Marie-Claire, Antignac, Corinne
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2004
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343810/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701729/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.550-560.2004
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