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Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice

Podocytes are specialized epithelial cells covering the basement membrane of the glomerulus in the kidney. The molecular mechanisms underlying the role of podocytes in glomerular filtration are still largely unknown. We generated podocin-deficient (Nphs2(−/−)) mice to investigate the function of pod...

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Tallennettuna:
Julkaisussa:Mol Cell Biol
Päätekijät: Roselli, Séverine, Heidet, Laurence, Sich, Mireille, Henger, Anna, Kretzler, Matthias, Gubler, Marie-Claire, Antignac, Corinne
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2004
Aiheet:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343810/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701729/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.550-560.2004
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