Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice

Podocytes are specialized epithelial cells covering the basement membrane of the glomerulus in the kidney. The molecular mechanisms underlying the role of podocytes in glomerular filtration are still largely unknown. We generated podocin-deficient (Nphs2(−/−)) mice to investigate the function of pod...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Roselli, Séverine, Heidet, Laurence, Sich, Mireille, Henger, Anna, Kretzler, Matthias, Gubler, Marie-Claire, Antignac, Corinne
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2004
Fag:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.550-560.2004
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