Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice

Podocytes are specialized epithelial cells covering the basement membrane of the glomerulus in the kidney. The molecular mechanisms underlying the role of podocytes in glomerular filtration are still largely unknown. We generated podocin-deficient (Nphs2(−/−)) mice to investigate the function of pod...

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में प्रकाशित:	Mol Cell Biol
मुख्य लेखकों:	Roselli, Séverine, Heidet, Laurence, Sich, Mireille, Henger, Anna, Kretzler, Matthias, Gubler, Marie-Claire, Antignac, Corinne
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Taylor & Francis 2004
विषय:	Mammalian Genetic Models with Minimal or Complex Phenotypes
ऑनलाइन पहुंच:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.550-560.2004
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