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Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter
Cystinosis is an inherited lysosomal storage disease characterized by defective transport of cystine out of lysosomes. However, the causative gene, CTNS, encodes a seven transmembrane domain lysosomal protein, cystinosin, unrelated to known transporters. To investigate the molecular function of cyst...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125690/ https://ncbi.nlm.nih.gov/pubmed/11689434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.21.5940 |
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