Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter
Cystinosis is an inherited lysosomal storage disease characterized by defective transport of cystine out of lysosomes. However, the causative gene, CTNS, encodes a seven transmembrane domain lysosomal protein, cystinosin, unrelated to known transporters. To investigate the molecular function of cyst...
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| Publicado en: | EMBO J |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125690/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11689434/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.21.5940 |
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