Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice

Podocytes are specialized epithelial cells covering the basement membrane of the glomerulus in the kidney. The molecular mechanisms underlying the role of podocytes in glomerular filtration are still largely unknown. We generated podocin-deficient (Nphs2(−/−)) mice to investigate the function of pod...

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Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Roselli, Séverine, Heidet, Laurence, Sich, Mireille, Henger, Anna, Kretzler, Matthias, Gubler, Marie-Claire, Antignac, Corinne
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 2004
Subjects:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.550-560.2004
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