Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice

Podocytes are specialized epithelial cells covering the basement membrane of the glomerulus in the kidney. The molecular mechanisms underlying the role of podocytes in glomerular filtration are still largely unknown. We generated podocin-deficient (Nphs2(−/−)) mice to investigate the function of pod...

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Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Mol Cell Biol
Prif Awduron:	Roselli, Séverine, Heidet, Laurence, Sich, Mireille, Henger, Anna, Kretzler, Matthias, Gubler, Marie-Claire, Antignac, Corinne
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Taylor & Francis 2004
Pynciau:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC343810/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14701729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.2.550-560.2004
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