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Oxidation of Dihydrotestosterone by Human Cytochromes P450 19A1 and 3A4

Dihydrotestosterone is a more potent androgen than testosterone and plays an important role in endocrine function. We demonstrated that, like testosterone, dihydrotestosterone can be oxidized by human cytochrome P450 (P450) 19A1, the steroid aromatase. The products identified include the 19-hydroxy-...

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Hlavní autoři: Cheng, Qian, Sohl, Christal D., Yoshimoto, Francis K., Guengerich, F. Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436178/
https://ncbi.nlm.nih.gov/pubmed/22773874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390047
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