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Oxidation of Dihydrotestosterone by Human Cytochromes P450 19A1 and 3A4
Dihydrotestosterone is a more potent androgen than testosterone and plays an important role in endocrine function. We demonstrated that, like testosterone, dihydrotestosterone can be oxidized by human cytochrome P450 (P450) 19A1, the steroid aromatase. The products identified include the 19-hydroxy-...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3436178/ https://ncbi.nlm.nih.gov/pubmed/22773874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390047 |
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