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Oxidation of Dihydrotestosterone by Human Cytochromes P450 19A1 and 3A4

Dihydrotestosterone is a more potent androgen than testosterone and plays an important role in endocrine function. We demonstrated that, like testosterone, dihydrotestosterone can be oxidized by human cytochrome P450 (P450) 19A1, the steroid aromatase. The products identified include the 19-hydroxy-...

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Detaylı Bibliyografya
Asıl Yazarlar: Cheng, Qian, Sohl, Christal D., Yoshimoto, Francis K., Guengerich, F. Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436178/
https://ncbi.nlm.nih.gov/pubmed/22773874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.390047
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