Kinetic Analysis of the Three-step Steroid Aromatase Reaction of Human Cytochrome P450 19A1

Por Sohl, Christal D., Guengerich, F. Peter
Publicado em 2010

Multi-step oxidations catalyzed by cytochrome P450 enzymes: Processive vs. distributive kinetics and the issue of carbonyl oxidation in chemical mechanisms

Por Guengerich, F. Peter, Sohl, Christal D., Chowdhury, Goutam
Publicado em 2010

High-throughput fluorescence assay of cytochrome P450 3A4

Por Cheng, Qian, Sohl, Christal D, Guengerich, F Peter
Publicado em 2009

Chromatographic assays of drug oxidation by human cytochrome P450 3A4

Por Sohl, Christal D, Cheng, Qian, Guengerich, F Peter
Publicado em 2009

Pools and Pols: Mechanism of a mutator phenotype

Por Sohl, Christal D., Ray, Sreerupa, Sweasy, Joann B.
Publicado no Proc Natl Acad Sci U S A (2015)

Mutations in human DNA polymerase γ confer unique mechanisms of catalytic deficiency that mirror the disease severity in mitochondrial disorder patients

Por Sohl, Christal D., Kasiviswanathan, Rajesh, Copeland, William C., Anderson, Karen S.
Publicado em 2013

Oxidation of Dihydrotestosterone by Human Cytochromes P450 19A1 and 3A4

Por Cheng, Qian, Sohl, Christal D., Yoshimoto, Francis K., Guengerich, F. Peter
Publicado em 2012

Measurement of cytochrome P450 and NADPH–cytochrome P450 reductase

Por Guengerich, F Peter, Martin, Martha V, Sohl, Christal D, Cheng, Qian
Publicado em 2009

Cooperativity of cytochrome P450 1A2: Interactions of 1,4-phenylene diisocyanide and 1-isopropoxy-4-nitrobenzene

Por Isin, Emre M., Sohl, Christal D., Eoff, Robert L., Guengerich, F. Peter
Publicado no Arch Biochem Biophys (2008)

Illuminating the Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance for the FGFR1 Gatekeeper Mutation: The Achilles’ Heel of Targeted Therapy

Por Sohl, Christal D., Ryan, Molly R., Luo, BeiBei, Frey, Kathleen M., Anderson, Karen S.
Publicado no ACS Chem Biol (2015)

Probing the molecular mechanism of action of the HIV-1 reverse transcriptase inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) using pre-steady-state kinetics

Por Muftuoglu, Yagmur, Sohl, Christal D., Mislak, Andrea C., Mitsuya, Hiroaki, Sarafianos, Stefan G., Anderson, Karen S.
Publicado em 2014

Fluorescence Resonance Energy Transfer Studies of DNA Polymerase β: THE CRITICAL ROLE OF FINGERS DOMAIN MOVEMENTS AND A NOVEL NON-COVALENT STEP DURING NUCLEOTIDE SELECTION

Por Towle-Weicksel, Jamie B., Dalal, Shibani, Sohl, Christal D., Doublié, Sylvie, Anderson, Karen S., Sweasy, Joann B.
Publicado em 2014

Mechanism of Interaction of Human Mitochondrial DNA Polymerase γ with the Novel Nucleoside Reverse Transcriptase Inhibitor 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine Indicates a Low Pot...

Por Sohl, Christal D., Singh, Kamlendra, Kasiviswanathan, Rajesh, Copeland, William C., Mitsuya, Hiroaki, Sarafianos, Stefan G., Anderson, Karen S.
Publicado em 2012

Balancing Antiviral Potency and Host Toxicity: Identifying a Nucleotide Inhibitor with an Optimal Kinetic Phenotype for HIV-1 Reverse Transcriptase

Por Sohl, Christal D., Kasiviswanathan, Rajesh, Kim, Jiae, Pradere, Ugo, Schinazi, Raymond F., Copeland, William C., Mitsuya, Hiroaki, Baba, Masanori, Anderson, Karen S.
Publicado em 2012

Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase γ

Por Sohl, Christal D., Szymanski, Michal R., Mislak, Andrea C., Shumate, Christie K., Amiralaei, Sheida, Schinazi, Raymond F., Anderson, Karen S., Yin, Y. Whitney
Publicado no Proc Natl Acad Sci U S A (2015)