Fluorescence Resonance Energy Transfer Studies of DNA Polymerase β: THE CRITICAL ROLE OF FINGERS DOMAIN MOVEMENTS AND A NOVEL NON-COVALENT STEP DURING NUCLEOTIDE SELECTION

During DNA repair, DNA polymerase β (Pol β) is a highly dynamic enzyme that is able to select the correct nucleotide opposite a templating base from a pool of four different deoxynucleoside triphosphates (dNTPs). To gain insight into nucleotide selection, we use a fluorescence resonance energy trans...

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Detalhes bibliográficos
Main Authors: Towle-Weicksel, Jamie B., Dalal, Shibani, Sohl, Christal D., Doublié, Sylvie, Anderson, Karen S., Sweasy, Joann B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047420/
https://ncbi.nlm.nih.gov/pubmed/24764311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.561878
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