Defective Nucleotide Release by DNA Polymerase Beta Mutator Variant E288K is the Basis of Its Low Fidelity

Eitemau Tebyg

• The E295K Cancer Variant of Human Polymerase β Favors the Mismatch Conformational Pathway during Nucleotide Selection
  gan: Eckenroth, Brian E., et al.
  Cyhoeddwyd: (2013)
• I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity
  gan: Liptak, Cary, et al.
  Cyhoeddwyd: (2018)
• The nature of the DNA substrate influences pre-catalytic conformational changes of DNA polymerase β
  gan: Huang, Ji, et al.
  Cyhoeddwyd: (2018)
• Remote Mutations Induce Functional Changes in Active Site Residues of Human DNA Polymerase β
  gan: Eckenroth, Brian E., et al.
  Cyhoeddwyd: (2017)
• Fluorescence Resonance Energy Transfer Studies of DNA Polymerase β: THE CRITICAL ROLE OF FINGERS DOMAIN MOVEMENTS AND A NOVEL NON-COVALENT STEP DURING NUCLEOTIDE SELECTION
  gan: Towle-Weicksel, Jamie B., et al.
  Cyhoeddwyd: (2014)