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I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity
DNA polymerase β (pol β) fills single nucleotide gaps in DNA during base excision repair and non-homologous end-joining. Pol β must select the correct nucleotide from among a pool of four nucleotides with similar structures and properties in order to maintain genomic stability during DNA repair. Her...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6237750/ https://ncbi.nlm.nih.gov/pubmed/30239932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky825 |
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