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Kinetic Analysis of the Three-step Steroid Aromatase Reaction of Human Cytochrome P450 19A1
Cytochrome P450 19A1 (P450 19A1), the aromatase, catalyzes the conversion of androgens to estrogens through a sequential three-step reaction, generating 19-hydroxy and 19-aldehyde intermediates en route to the product estrogen. A procedure for the heterologous expression and purification of P450 19A...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878537/ https://ncbi.nlm.nih.gov/pubmed/20385561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.123711 |
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