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Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions

Cytochrome P450 (P450, CYP) research provides many opportunities for the application of kinetic isotope effect (KIE) strategies. P450s collectively catalyze oxidations of more substrates than any other group of enzymes, and C-H bond cleavage is a major feature in a large fraction of these reactions....

詳細記述

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書誌詳細
出版年:Methods Enzymol
第一著者: Guengerich, F. Peter
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776663/
https://ncbi.nlm.nih.gov/pubmed/28911772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.06.036
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