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Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions
Cytochrome P450 (P450, CYP) research provides many opportunities for the application of kinetic isotope effect (KIE) strategies. P450s collectively catalyze oxidations of more substrates than any other group of enzymes, and C-H bond cleavage is a major feature in a large fraction of these reactions....
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| 出版年: | Methods Enzymol |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776663/ https://ncbi.nlm.nih.gov/pubmed/28911772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.06.036 |
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