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Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions

Cytochrome P450 (P450, CYP) research provides many opportunities for the application of kinetic isotope effect (KIE) strategies. P450s collectively catalyze oxidations of more substrates than any other group of enzymes, and C-H bond cleavage is a major feature in a large fraction of these reactions....

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Foilsithe in:Methods Enzymol
Príomhúdar: Guengerich, F. Peter
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776663/
https://ncbi.nlm.nih.gov/pubmed/28911772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.06.036
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