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Kinetic Modeling of Steady-State Situations in Cytochrome P450 Enzyme Reactions
In the course of investigations of the kinetics of individual reactions of cytochrome P450 (P450) enzymes, a number of points about the complexity of P450 enzyme kinetics have become apparent. Several of these are of particular relevance to work with P450 enzymes in the course of drug development an...
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| Publicat a: | Drug Metab Dispos |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6815944/ https://ncbi.nlm.nih.gov/pubmed/31427434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.119.088732 |
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