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Cytochrome P450s and other enzymes in drug metabolism and toxicity
The cytochrome P450 (P450) enzymes are the major catalysts involved in the metabolism of drugs. bioavailability and toxicity are 2 of the most common barriers in drug development today, and P450 and the conjugation enzymes can influence these effects. The toxicity of drugs can be considered in 5 con...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
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Springer-Verlag
2006
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751428/ https://ncbi.nlm.nih.gov/pubmed/16584116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080112 |
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