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Sulfenylation of Human Liver and Kidney Microsomal Cytochromes P450 and Other Drug-Metabolizing Enzymes as a Response to Redox Alteration

The lumen of the endoplasmic reticulum (ER) provides an oxidizing environment to aid in the formation of disulfide bonds, which is tightly regulated by both antioxidant proteins and small molecules. On the cytoplasmic side of the ER, cytochrome P450 (P450) proteins have been identified as a superfam...

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Dades bibliogràfiques
Publicat a:Mol Cell Proteomics
Autors principals: Albertolle, Matthew E., Phan, Thanh T. N., Pozzi, Ambra, Guengerich, F. Peter
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5930400/
https://ncbi.nlm.nih.gov/pubmed/29374135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.RA117.000382
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