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Kinetic Deuterium Isotope Effects in Cytochrome P450 Reactions
Cytochrome P450 (P450, CYP) research provides many opportunities for the application of kinetic isotope effect (KIE) strategies. P450s collectively catalyze oxidations of more substrates than any other group of enzymes, and C-H bond cleavage is a major feature in a large fraction of these reactions....
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| Publicat a: | Methods Enzymol |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776663/ https://ncbi.nlm.nih.gov/pubmed/28911772 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2017.06.036 |
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