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Suppression of Cancer Progression by MGAT1 shRNA Knockdown

Oncogenic signaling promotes tumor invasion and metastasis, in part, by increasing the expression of tri- and tetra- branched N-glycans. The branched N-glycans bind to galectins forming a multivalent lattice that enhances cell surface residency of growth factor receptors, and focal adhesion turnover...

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書誌詳細
主要な著者: Beheshti Zavareh, Reza, Sukhai, Mahadeo A., Hurren, Rose, Gronda, Marcela, Wang, Xiaoming, Simpson, Craig D., Maclean, Neil, Zih, Francis, Ketela, Troy, Swallow, Carol J., Moffat, Jason, Rose, David R., Schachter, Harry, Schimmer, Aaron D., Dennis, James W.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434202/
https://ncbi.nlm.nih.gov/pubmed/22957033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043721
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