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Suppression of Cancer Progression by MGAT1 shRNA Knockdown
Oncogenic signaling promotes tumor invasion and metastasis, in part, by increasing the expression of tri- and tetra- branched N-glycans. The branched N-glycans bind to galectins forming a multivalent lattice that enhances cell surface residency of growth factor receptors, and focal adhesion turnover...
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| 主要な著者: | , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2012
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3434202/ https://ncbi.nlm.nih.gov/pubmed/22957033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043721 |
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