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Criteria for effective design, construction, and gene knockdown by shRNA vectors

BACKGROUND: RNA interference (RNAi) technology is a powerful methodology recently developed for the specific knockdown of targeted genes. RNAi is most commonly achieved either transiently by transfection of small interfering (si) RNA oligonucleotides, or stably using short hairpin (sh) RNA expressed...

תיאור מלא

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מידע ביבליוגרפי
Main Authors: Taxman, Debra J, Livingstone, Laura R, Zhang, Jinghua, Conti, Brian J, Iocca, Heather A, Williams, Kristi L, Lich, John D, Ting, Jenny P-Y, Reed, William
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2006
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409772/
https://ncbi.nlm.nih.gov/pubmed/16433925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-6-7
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