Criteria for effective design, construction, and gene knockdown by shRNA vectors

BACKGROUND: RNA interference (RNAi) technology is a powerful methodology recently developed for the specific knockdown of targeted genes. RNAi is most commonly achieved either transiently by transfection of small interfering (si) RNA oligonucleotides, or stably using short hairpin (sh) RNA expressed...

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書誌詳細
主要な著者: Taxman, Debra J, Livingstone, Laura R, Zhang, Jinghua, Conti, Brian J, Iocca, Heather A, Williams, Kristi L, Lich, John D, Ting, Jenny P-Y, Reed, William
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2006
主題:
Methodology Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1409772/
https://ncbi.nlm.nih.gov/pubmed/16433925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-6-7
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