Suppression of Cancer Progression by MGAT1 shRNA Knockdown

Oncogenic signaling promotes tumor invasion and metastasis, in part, by increasing the expression of tri- and tetra- branched N-glycans. The branched N-glycans bind to galectins forming a multivalent lattice that enhances cell surface residency of growth factor receptors, and focal adhesion turnover...

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Detalhes bibliográficos
Main Authors: Beheshti Zavareh, Reza, Sukhai, Mahadeo A., Hurren, Rose, Gronda, Marcela, Wang, Xiaoming, Simpson, Craig D., Maclean, Neil, Zih, Francis, Ketela, Troy, Swallow, Carol J., Moffat, Jason, Rose, David R., Schachter, Harry, Schimmer, Aaron D., Dennis, James W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434202/
https://ncbi.nlm.nih.gov/pubmed/22957033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043721
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