Suppression of Cancer Progression by MGAT1 shRNA Knockdown

Oncogenic signaling promotes tumor invasion and metastasis, in part, by increasing the expression of tri- and tetra- branched N-glycans. The branched N-glycans bind to galectins forming a multivalent lattice that enhances cell surface residency of growth factor receptors, and focal adhesion turnover...

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Bibliografiska uppgifter
Huvudupphovsmän: Beheshti Zavareh, Reza, Sukhai, Mahadeo A., Hurren, Rose, Gronda, Marcela, Wang, Xiaoming, Simpson, Craig D., Maclean, Neil, Zih, Francis, Ketela, Troy, Swallow, Carol J., Moffat, Jason, Rose, David R., Schachter, Harry, Schimmer, Aaron D., Dennis, James W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2012
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3434202/
https://ncbi.nlm.nih.gov/pubmed/22957033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043721
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