Homogentisate 1,2 Dioxygenase is Expressed in Human Osteoarticular Cells: Implications in Alkaptonuria

Alkaptonuria (AKU) results from defective homogentisate1,2-dioxygenase (HGD), causing degenerative arthropathy. The deposition of ochronotic pigment in joints is so far attributed to homogentisic acid produced by the liver, circulating in the blood and accumulating locally. Human normal and AKU oste...

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Bibliografiska uppgifter
Huvudupphovsmän: Laschi, Marcella, Tinti, Laura, Braconi, Daniela, Millucci, Lia, Ghezzi, Lorenzo, Amato, Loredana, Selvi, Enrico, Spreafico, Adriano, Bernardini, Giulia, Santucci, Annalisa
Materialtyp: Artigo
Språk:Inglês
Publicerad: Wiley Subscription Services, Inc., A Wiley Company 2012
Ämnen:
Original Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427883/
https://ncbi.nlm.nih.gov/pubmed/22105303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24018
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