Antioxidants inhibit SAA formation and pro-inflammatory cytokine release in a human cell model of alkaptonuria

Objective. Alkaptonuria (AKU) is an ultra-rare autosomal recessive disease that currently lacks an appropriate therapy. Recently we provided experimental evidence that AKU is a secondary serum amyloid A (SAA)-based amyloidosis. The aim of the present work was to evaluate the use of antioxidants to i...

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Detalhes bibliográficos
Main Authors: Spreafico, Adriano, Millucci, Lia, Ghezzi, Lorenzo, Geminiani, Michela, Braconi, Daniela, Amato, Loredana, Chellini, Federico, Frediani, Bruno, Moretti, Elena, Collodel, Giulia, Bernardini, Giulia, Santucci, Annalisa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Clinical Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3741479/
https://ncbi.nlm.nih.gov/pubmed/23704321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/ket185
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