Biochemical and Proteomic Characterization of Alkaptonuric Chondrocytes

Alkaptonuria (AKU) is a rare genetic disease associated with the accumulation of homogentisic acid (HGA) and its oxidized/polymerized products which leads to the deposition of melanin-like pigments (ochronosis) in connective tissues. Although numerous case reports have described ochronosis in joints...

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Bibliographische Detailangaben
Hauptverfasser: Braconi, Daniela, Bernardini, Giulia, Bianchini, Claretta, Laschi, Marcella, Millucci, Lia, Amato, Loredana, Tinti, Laura, Serchi, Tommaso, Chellini, Federico, Spreafico, Adriano, Santucci, Annalisa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2012
Schlagworte:
Original Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427902/
https://ncbi.nlm.nih.gov/pubmed/22213341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24033
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