ロード中...
Chemoenzymatic Glycoengineering of Intact IgG Antibodies for Gain of Functions
The fine structures of Fc N-glycans can modulate the effector functions of IgG antibodies. It has been demonstrated that lack of the core fucose on the Fc N-glycans leads to drastic enhancement of antibody-dependent cellular cytotoxicity (ADCC), while terminal α2,6-sialylation of Fc glycan plays a c...
保存先:
| 主要な著者: | , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427744/ https://ncbi.nlm.nih.gov/pubmed/22747414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3051266 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|