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G(s)α Deficiency in the Paraventricular Nucleus of the Hypothalamus Partially Contributes to Obesity Associated with G(s)α Mutations

The G protein α-subunit G(s)α mediates receptor-stimulated cAMP generation. Heterozygous inactivating G(s)α mutations on the maternal allele result in obesity primarily due to reduced energy expenditure in Albright hereditary osteodystrophy patients and in mice. We previously showed that mice with c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, Min, Berger, Alta, Kablan, Ahmed, Zhang, Jiandi, Gavrilova, Oksana, Weinstein, Lee S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Endocrine Society 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423628/
https://ncbi.nlm.nih.gov/pubmed/22733970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1113
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