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G(s)α Deficiency in the Paraventricular Nucleus of the Hypothalamus Partially Contributes to Obesity Associated with G(s)α Mutations

The G protein α-subunit G(s)α mediates receptor-stimulated cAMP generation. Heterozygous inactivating G(s)α mutations on the maternal allele result in obesity primarily due to reduced energy expenditure in Albright hereditary osteodystrophy patients and in mice. We previously showed that mice with c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Min, Berger, Alta, Kablan, Ahmed, Zhang, Jiandi, Gavrilova, Oksana, Weinstein, Lee S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Endocrine Society 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3423628/
https://ncbi.nlm.nih.gov/pubmed/22733970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1113
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