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G(q)α/G(11)α deficiency in dorsomedial hypothalamus leads to obesity resulting from decreased energy expenditure and impaired sympathetic nerve activity
The G-protein subunits G(q)α and G(11)α (G(q/11)α) couple receptors to phospholipase C, leading to increased intracellular calcium. In this study we investigated the consequences of G(q)/(11)α deficiency in the dorsomedial hypothalamus (DMH), a critical site for the control of energy homeostasis. Mi...
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| Veröffentlicht in: | Am J Physiol Endocrinol Metab |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8260363/ https://ncbi.nlm.nih.gov/pubmed/33166186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00059.2020 |
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