A Designer Bleomycin with Significantly Improved DNA Cleavage Activity

The bleomycins (BLMs) are used clinically in combination with a number of other agents for the treatment of several types of tumors, and the BLM, etoposide, and cisplatin treatment regimen cures 90–95% of metastatic testicular cancer patients. BLM-induced pneumonitis is the most feared, dose-limitin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, Sheng-Xiong, Feng, Zhiyang, Wang, Liyan, Galm, Ute, Wendt-Pienkowski, Evelyn, Yang, Dong, Tao, Meifeng, Coughlin, Jane M, Duan, Yanwen, Shen, Ben
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422780/
https://ncbi.nlm.nih.gov/pubmed/22831455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3056535
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