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AIDing antibody diversity by error-prone mismatch repair
The creation of a highly diverse antibody repertoire requires the synergistic activity of a DNA mutator, known as activation-induced deaminase (AID), coupled with an error-prone repair process that recognizes the DNA mismatch catalyzed by AID. Instead of facilitating the canonical error-free respons...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3422444/ https://ncbi.nlm.nih.gov/pubmed/22703640 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smim.2012.05.005 |
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