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Mouse models of DNA mismatch repair in cancer research
Germline mutations in DNA mismatch repair (MMR) genes are the cause of hereditary non-polyposis colorectal cancer/Lynch syndrome (HNPCC/LS) one of the most common cancer predisposition syndromes, and defects in MMR are also prevalent in sporadic colorectal cancers. In the past, the generation and an...
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| izdano v: | DNA Repair (Amst) |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4754788/ https://ncbi.nlm.nih.gov/pubmed/26708047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.11.015 |
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