Llwytho...

Mismatch-mediated error prone repair at the Immunoglobulin genes

The generation of effective antibodies depends upon somatic hypermutation (SHM) and class-switch recombination (CSR) of antibody genes by activation induced cytidine deaminase (AID) and the subsequent recruitment of error prone base excision and mismatch repair. While AID initiates and is required f...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chahwan, Richard, Edelmann, Winfried, Scharff, Matthew D, Roa, Sergio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3235044/
https://ncbi.nlm.nih.gov/pubmed/22100214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2011.09.001
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