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Mismatch-mediated error prone repair at the Immunoglobulin genes
The generation of effective antibodies depends upon somatic hypermutation (SHM) and class-switch recombination (CSR) of antibody genes by activation induced cytidine deaminase (AID) and the subsequent recruitment of error prone base excision and mismatch repair. While AID initiates and is required f...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235044/ https://ncbi.nlm.nih.gov/pubmed/22100214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopha.2011.09.001 |
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