A carregar...
MSH2/MSH6 Complex Promotes Error-Free Repair of AID-Induced dU:G Mispairs as well as Error-Prone Hypermutation of A:T Sites
Mismatch repair of AID-generated dU:G mispairs is critical for class switch recombination (CSR) and somatic hypermutation (SHM) in B cells. The generation of a previously unavailable Msh2(−/−)Msh6(−/−) mouse has for the first time allowed us to examine the impact of the complete loss of MutSα on lym...
Na minha lista:
| Main Authors: | , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2887398/ https://ncbi.nlm.nih.gov/pubmed/20567595 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011182 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|