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Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
PTEN is a tumor suppressor gene mutated in various advanced human neoplasias, including glioblastomas and prostate, breast, endometrial, and kidney cancers. This tumor suppressor is a lipid phosphatase that negatively regulates cell survival and proliferation mediated by phosphatidylinositol 3-kinas...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2004
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341836/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14747659/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308217100 |
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