Prostaglandin E(2) Inhibits Fibroblast Migration by E-Prostanoid 2 Receptor–Mediated Increase in PTEN Activity

An increased migratory phenotype exists in lung fibroblasts derived from patients with fibroproliferative lung disease. Prostaglandin E(2) (PGE(2)) suppresses fibroblast migration, but the receptor(s) and mechanism(s) mediating this action are unknown. Our data confirm that treatment of human lung f...

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Hlavní autoři: White, Eric S., Atrasz, Rachelle G., Dickie, Emily G., Aronoff, David M., Stambolic, Vuk, Mak, Tak W., Moore, Bethany B., Peters-Golden, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1965457/
https://ncbi.nlm.nih.gov/pubmed/15539459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2004-0126OC
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