Prostaglandin E(2) suppresses allergic sensitization and lung inflammation by targeting the E prostanoid 2 receptor on T cells

BACKGROUND: Endogenous prostanoids have been suggested to modulate sensitization during experimental allergic asthma, but the specific role of prostaglandin E(2) (PGE(2)) or of specific E prostanoid (EP) receptors is not known. OBJECTIVE: Here we tested the role of EP2 signaling in allergic asthma....

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Main Authors: Zaslona, Zbigniew, Okunishi, Katsuhide, Bourdonnay, Emilie, Domingo-Gonzalez, Racquel, Moore, Bethany B., Lukacs, Nicholas W., Aronoff, David M., Peters-Golden, Marc
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960315/
https://ncbi.nlm.nih.gov/pubmed/24075232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2013.07.037
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