Distinct Protein Kinase A Anchoring Proteins Direct Prostaglandin E(2) Modulation of Toll-like Receptor Signaling in Alveolar Macrophages

Toll-like receptors (TLRs) direct a proinflammatory program in macrophages. One mediator whose generation is induced by TLR ligation is prostaglandin E(2) (PGE(2)), which is well known to increase intracellular cAMP upon G protein-coupled receptor ligation. How PGE(2)/cAMP shapes the nascent TLR res...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Kim, Sang-Hoon, Serezani, Carlos Henrique, Okunishi, Katsuhide, Zaslona, Zbigniew, Aronoff, David M., Peters-Golden, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058957/
https://ncbi.nlm.nih.gov/pubmed/21247892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.187815
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge