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Effects of prostaglandin E(2) on the subcellular localization of Epac-1 and Rap1 proteins during Fcγ receptor mediated phagocytosis in alveolar macrophages
Recent studies have demonstrated a central role for the exchange protein activated by cAMP (Epac) in the inhibition of Fcγ-receptor mediated phagocytosis and bacterial killing by prostaglandin E(2) (PGE(2)) in macrophages. However, the subcellular localization of Epac, and its primary target Rap1, h...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2390918/ https://ncbi.nlm.nih.gov/pubmed/18021770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.10.011 |
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