Rap1 Activation Is Required for Fcγ Receptor-Dependent Phagocytosis

Phagocytosis of IgG-opsonized microbes via the Fcγ receptor (FcγR) requires the precise coordination of a number of signaling molecules, including the low-molecular mass GTPases. Little is known about the Ras-family GTPase Rap1 in this process. We therefore investigated its importance in mediating F...

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Autori principali: Chung, Jooho, Serezani, Carlos H., Huang, Steven K., Stern, Joel N. H., Keskin, Derin B., Jagirdar, Rajesh, Brock, Thomas G., Aronoff, David M., Peters-Golden, Marc
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077557/
https://ncbi.nlm.nih.gov/pubmed/18832707
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