FcγRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions

Leukotriene (LT) B(4) is generated in response to engagement of the Fcγ receptor (FcγR) and potently contributes to FcγR-mediated antimicrobial functions in pulmonary alveolar macrophages. In this study, we report that the LTB(4) receptor leukotriene B(4) receptor 1 (BLT1) redistributes from nonlipi...

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Hlavní autoři: Serezani, Carlos H., Aronoff, David M., Sitrin, Robert G., Peters-Golden, Marc
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2009
Témata:
Phagocytes, Granulocytes, and Myelopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759654/
https://ncbi.nlm.nih.gov/pubmed/19657115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-01-199919
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