Red pulp macrophages in the human spleen are a distinct cell population with a unique expression of Fc-γ receptors

Tissue-resident macrophages in the spleen play a major role in the clearance of immunoglobulin G (IgG)–opsonized blood cells, as occurs in immune thrombocytopenia (ITP) and autoimmune hemolytic anemia (AIHA). Blood cells are phagocytosed via the Fc-γ receptors (FcγRs), but little is known about the...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Nagelkerke, Sietse Q., Bruggeman, Christine W., den Haan, Joke M. M., Mul, Erik P. J., van den Berg, Timo K., van Bruggen, Robin, Kuijpers, Taco W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916003/
https://ncbi.nlm.nih.gov/pubmed/29692344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017015008
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