Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair

Myeloid-derived suppressor cells (MDSCs) have the capacity to suppress T-cell–mediated immune responses and impact the clinical outcome of cancer, infections, and transplantation settings. Although MDSCs were initially described as bone marrow–derived immature myeloid cells (either monocytic or gran...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Aarts, Cathelijn E. M., Hiemstra, Ida H., Béguin, Eelke P., Hoogendijk, Arjan J., Bouchmal, Souhailla, van Houdt, Michel, Tool, Anton T. J., Mul, Erik, Jansen, Machiel H., Janssen, Hans, van Alphen, Floris P. J., de Boer, Jan-Paul, Zuur, Charlotte L., Meijer, Alexander B., van den Berg, Timo K., Kuijpers, Taco W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880908/
https://ncbi.nlm.nih.gov/pubmed/31738831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019031609
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