Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair

Myeloid-derived suppressor cells (MDSCs) have the capacity to suppress T-cell–mediated immune responses and impact the clinical outcome of cancer, infections, and transplantation settings. Although MDSCs were initially described as bone marrow–derived immature myeloid cells (either monocytic or gran...

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Vydáno v:Blood Adv
Hlavní autoři: Aarts, Cathelijn E. M., Hiemstra, Ida H., Béguin, Eelke P., Hoogendijk, Arjan J., Bouchmal, Souhailla, van Houdt, Michel, Tool, Anton T. J., Mul, Erik, Jansen, Machiel H., Janssen, Hans, van Alphen, Floris P. J., de Boer, Jan-Paul, Zuur, Charlotte L., Meijer, Alexander B., van den Berg, Timo K., Kuijpers, Taco W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2019
Témata:
Phagocytes, Granulocytes, and Myelopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880908/
https://ncbi.nlm.nih.gov/pubmed/31738831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019031609
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