Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair

Myeloid-derived suppressor cells (MDSCs) have the capacity to suppress T-cell–mediated immune responses and impact the clinical outcome of cancer, infections, and transplantation settings. Although MDSCs were initially described as bone marrow–derived immature myeloid cells (either monocytic or gran...

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Enregistré dans:
Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Aarts, Cathelijn E. M., Hiemstra, Ida H., Béguin, Eelke P., Hoogendijk, Arjan J., Bouchmal, Souhailla, van Houdt, Michel, Tool, Anton T. J., Mul, Erik, Jansen, Machiel H., Janssen, Hans, van Alphen, Floris P. J., de Boer, Jan-Paul, Zuur, Charlotte L., Meijer, Alexander B., van den Berg, Timo K., Kuijpers, Taco W.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2019
Sujets:
Phagocytes, Granulocytes, and Myelopoiesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6880908/
https://ncbi.nlm.nih.gov/pubmed/31738831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019031609
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