Effects of prostaglandin E(2) on the subcellular localization of Epac-1 and Rap1 proteins during Fcγ receptor mediated phagocytosis in alveolar macrophages

Recent studies have demonstrated a central role for the exchange protein activated by cAMP (Epac) in the inhibition of Fcγ-receptor mediated phagocytosis and bacterial killing by prostaglandin E(2) (PGE(2)) in macrophages. However, the subcellular localization of Epac, and its primary target Rap1, h...

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Main Authors: Brock, Thomas G., Serezani, Carlos H., Carstens, Jennifer K., Peters-Golden, Marc, Aronoff, David M.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2390918/
https://ncbi.nlm.nih.gov/pubmed/18021770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.10.011
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