Prostaglandin E(2) Mediates IL-1β-Related Fibroblast Mitogenic Effects in Acute Lung Injury through Differential Utilization of Prostanoid Receptors

The fibroproliferative response to acute lung injury (ALI) results in severe, persistent respiratory dysfunction. We have reported that IL-1β is elevated in pulmonary edema fluid in those with ALI and mediates an autocrine-acting, fibroblast mitogenic pathway. In this study, we examine the role of I...

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Main Authors: White, Kimberly E., Ding, Qiang, Moore, Bethany B., Peters-Golden, Marc, Ware, Lorraine B., Matthay, Michael A., Olman, Mitchell A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789491/
https://ncbi.nlm.nih.gov/pubmed/18097066
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