Negative Regulation of Myofibroblast Differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10)

Rationale: Myofibroblasts are primary effector cells in idiopathic pulmonary fibrosis (IPF). Defining mechanisms of myofibroblast differentiation may be critical to the development of novel therapeutic agents. Objective: To show that myofibroblast differentiation is regulated by phosphatase and tens...

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Main Authors: White, Eric S., Atrasz, Rachelle G., Hu, Biao, Phan, Sem H., Stambolic, Vuk, Mak, Tak W., Hogaboam, Cory M., Flaherty, Kevin R., Martinez, Fernando J., Kontos, Christopher D., Toews, Galen B.
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2006
Teme:
F. Interstitial Lung Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434700/
https://ncbi.nlm.nih.gov/pubmed/16179636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200507-1058OC
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