Negative Regulation of Myofibroblast Differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10)

Rationale: Myofibroblasts are primary effector cells in idiopathic pulmonary fibrosis (IPF). Defining mechanisms of myofibroblast differentiation may be critical to the development of novel therapeutic agents. Objective: To show that myofibroblast differentiation is regulated by phosphatase and tens...

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Bibliographic Details
Main Authors: White, Eric S., Atrasz, Rachelle G., Hu, Biao, Phan, Sem H., Stambolic, Vuk, Mak, Tak W., Hogaboam, Cory M., Flaherty, Kevin R., Martinez, Fernando J., Kontos, Christopher D., Toews, Galen B.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2006
Subjects:
F. Interstitial Lung Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434700/
https://ncbi.nlm.nih.gov/pubmed/16179636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200507-1058OC
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