Negative Regulation of Myofibroblast Differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on Chromosome 10)

Rationale: Myofibroblasts are primary effector cells in idiopathic pulmonary fibrosis (IPF). Defining mechanisms of myofibroblast differentiation may be critical to the development of novel therapeutic agents. Objective: To show that myofibroblast differentiation is regulated by phosphatase and tens...

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Hlavní autoři: White, Eric S., Atrasz, Rachelle G., Hu, Biao, Phan, Sem H., Stambolic, Vuk, Mak, Tak W., Hogaboam, Cory M., Flaherty, Kevin R., Martinez, Fernando J., Kontos, Christopher D., Toews, Galen B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Thoracic Society 2006
Témata:
F. Interstitial Lung Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1434700/
https://ncbi.nlm.nih.gov/pubmed/16179636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200507-1058OC
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